Utilizing Bioluminescent and Fluorescent Probes in Animal Model Experiments

Utilizing bioluminescent and fluorescent probes in animal model experiments serves as a pivotal topic within the realm of functional imaging reagents. This field leverages cutting-edge technologies to enhance our understanding of complex biological processes in vivo. Bioluminescent probes, such as luciferin potassium salt and caged luciferin probes, offer unique advantages in tracking cellular and molecular activities with high sensitivity and low background noise. Fluorescent probes, including ICG NHS ester, further enable precise visualization in deep tissue imaging. The topic covers the historical evolution of these technologies, highlighting breakthroughs and contributions from key industry players. Detailed insights into various bioluminescent cell lines and the role of Luc2 lentiviral particles in creating stable expression systems are also provided. By delving into the advancements and practical applications of these probes, the content aims to equip biomedical researchers, pharmaceutical scientists, biotechnology executives, and other stakeholders with the knowledge to innovate and achieve impactful results in preclinical studies and drug development.